Detection of myelin oligodendrocyte glycoprotein antibody in pediatric patient with acute disseminated encephalomyelitis: a case report

Introduction: Acute Disseminated Encephalomyelitis (ADEM) is an immunity-mediated central nervous system demyelinating disorder. Myelin Oligodendrocyte Glycoprotein (MOG) examination provides information about a patient's ADEM development status. A positive MOG antibody can signify first episode or incomplete recovery. This review aims to report case of pediatric patient with acute disseminated encephalomyelitis antibody. Case Presentation: We present 5-year-old girl symptoms low-grade fever, encephalopathy, blurred vision, numb and tingling sensations on hands feet, weakness, unable walk. Head MRI (Magnetic Resonance Imaging) reveals lesions in the bilateral thalamus white matter left parietal lobe. There was also thickening optic nerves. Blood laboratory relatively normal, test positive. The then treated corticosteroids for 1 year had 2 recurrent episodes attacks. evaluation still 6 months after attack. After Intravenous immunoglobulin (IVIG) treatment given, resulting excellent clinical response no attack since then. Conclusions: cases have good prognosis IVIG administration, help other supportive therapy, improves recovery treating ADEM.